Temporal consistency within the metabolic correlation networks. The temporal systematics of different correlation networks has been determined via the consistency parameter θ as a function of parameter κ. Different values of parameter ω (see Methods) have been investigated. Negative values of θ indicate a strong anti-correlation between the similarity of two networks and the proximity of the sampling points in time, i.e. similar correlation networks are temporally close to each other. The regime enclosed by the gray-shaded box describes the statistically reliable region of κ with an average p-value of 0.09. The inset displays the correlation between the time difference Δt and network similarity σ for a selected value of threshold κ.
Müller-Linow et al. BMC Systems Biology 2007 1:44 doi:10.1186/1752-0509-1-44