Effect of PBS-citrate (control) (A), TiO2 (B) and ZnO (C) agglomerated engineered nanoparticles on canine platelet-rich plasma. Platelet-rich plasma was incubated with agglomerated engineered nanoparticles dissolved in phosphate buffer saline for 1 hour. Activated platelets (white arrow) and larger number of erythrocytes (gray arrow) including echinocytes can be seen in the sample incubated with ZnO (C).
Šimundić et al. BMC Veterinary Research 2013 9:7 doi:10.1186/1746-6148-9-7