Table 1

Blood parameters of healthy Pb-non-exposed birds and Cinereous Vultures (Aegypius monachus ) prior to and after therapy for lead toxicosis using CaNa2EDTA
Parameters  Groups of vultures
Pb-non-exposed Pre-treatment Post-treatment
Ca (mmol/l) 2.83 ± 0.35 2.74 ± 0.25 2.50 ± 0.35
P (mmol/l) 1.28 ± 0.15 1.30 ± 0.27 0.96 ± 0.35
Fe (μmol/l) 13.55 ± 3.27 10.57 ± 1.74 5.40 ± 2.65**
Hb (g/l) 147.00 ± 27.12 112.12 ± 19.85 132.71 ± 24.06
Ht (l/l) 0.50 ± 0.04 0.36 ± 0.06* 0.42 ± 0.08
TP (g/l) 35.51 ± 6.40 30.80 ± 5.49 32.21 ± 4.82
UAC (μmol/l) 578.85 ± 202.97 872.30 ± 35.43 731.85 ± 327.45
AST (μkat/l) 6.78 ± 1.54 7.81 ± 1.90 5.74 ± 2.77
ALP (μkat/l) 0.64 ± 0.21 1.00 ± 1.62 3.71 ± 1.34*
CK (μkat/l) 13.53 ± 6.58 41.04 ± 10.54* 10.63 ± 0.94
LDH (μkat/l) 7.82 ± 0.94 8.06 ± 4.81 13.17 ± 8.62
TBIL (μmol/l) 13.10 ± 2.29 10.60 ± 1.50 7.81 ± 2.48
TBARS (nmol/l) 1.94 ± 0.12 7.00 ± 0.80** 7.31 ± 0.45**
FRAP (μmol/l) 1619.41 ± 34.00 1046.22 ± 362.14** 1516.75 ± 451.43
MT (μg/mg protein) 1.43 ± 0.16 1.79 ± 0.40 1.92 ± 0.20*
GSH (μg/ml) 1.00 ± 0.05 1.07 ± 0.12 0.79 ± 0.03*
GSSG (μg/ml) 0.11 ± 0.04 0.05 ± 0.01* 0.01 ± 0.001**

Values represent mean ± SD; n = 6 in healthy Pb-non-exposed birds (3 males and 3 females), n = 8 in pre-and-post-treatment birds; * = p < 0.05, ** = p < 0.01 when compared against control group. The pre-and-post-treatment birds were blood sampled at the time of and one month after Ca-EDTA therapy, respectively. Ca = calcium, P = phosphorus, Fe = iron, Hb = haemoglobin, Ht = haematocrit, TP = total protein, UAC = uric acid, AST = aspartate aminotransferase, ALP = alkaline phosphatase, CK = creatine kinase, LDH = lactate dehydrogenase, TBIL = total bilirubin, TBARS = thiobarbituric acid reactive species, FRAP = ferric reducing ability of plasma, MT = metallothionein, GSH = reduced glutathione, GSSG = oxidised glutathione.

Pikula et al.

Pikula et al. BMC Veterinary Research 2013 9:11   doi:10.1186/1746-6148-9-11

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