Open Access Research article

Plasma levels of TNF-α, IFN-γ, IL-4 and IL-10 during a course of experimental contagious bovine pleuropneumonia

Flavio Sacchini1, Mirella Luciani1, Romolo Salini1, Massimo Scacchia1, Attilio Pini1, Rossella Lelli1, Jan Naessens2, Jane Poole2 and Joerg Jores2*

Author Affiliations

1 Istituto "G. Caporale", via Campo Boario, 64100 Teramo, Italy

2 International Livestock Research Institute, Old Naivasha Road, PO Box 30709, 00100 Nairobi, Kenya

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BMC Veterinary Research 2012, 8:44  doi:10.1186/1746-6148-8-44

Published: 25 April 2012

Additional files

Additional file 1:

Comparison of body temperatures of cattle showing acute and mild disease symptoms. Two groups of animals, which showed acute clinical symptoms (red) and mild clinical symptoms (blue) are displayed. Significant levels are marked (* = p < 0.05, ** = p < 0.01, *** = p < 0.001).

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Additional file 2:

TNF-α plasma concentrations in pg/ml.

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Additional file 3:

IFN-γ plasma concentrations in pg/ml.

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Additional file 4:

IL-4 plasma concentrations in pg/ml.

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Additional file 5:

IL-10 plasma concentrations in pg/ml.

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Additional file 6:

Observed qualitative Mycoplasma-specific antibody responses. The day of depletion of CD4+ T cells is indicated by a red triangle.

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