Open Access Research article

Molecular and epigenetic analysis of the fragile histidine triad tumour suppressor gene in equine sarcoids

Maria Strazzullo1, Annunziata Corteggio2, Gennaro Altamura2, Romina Francioso3, Franco Roperto2, Maurizio D'Esposito34 and Giuseppe Borzacchiello2*

  • * Corresponding author: Giuseppe Borzacchiello

  • † Equal contributors

Author Affiliations

1 Institute for Animal Production System in Mediterranean Environment, National Research Council, Via Argine, 1085, 80147 Naples, Italy

2 Department of Pathology and Animal Health, University of Naples Federico II, Via Veterinaria, 1, 80137 Naples, Italy

3 Institute of Genetic and Biophysics ABT, National Research Council, Via P. Castellino 111, 80131 Naples, Italy

4 IRCCS Neuromed, Pozzilli, Italy

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BMC Veterinary Research 2012, 8:30  doi:10.1186/1746-6148-8-30

Published: 16 March 2012

Additional files

Additional file 1:

Figure S1. Bisulfite sequencing of equine FHIT CpG island. In the top are summerised the CpG island (boxed) and the position of primers of the nested PCR. Circles below indicate methylation status: filled circles, methylated CpGs; open circles: unmethylated CpGs. Each row of circles corresponds to one clone. The number on top of circle is referred to CpG position and the column on the left is referred to number of indipendent clones sequenced.

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