Table 1

Scoring of the presence of macrophages, T- lymphocytes and B-lymphocytes in bronchus-associated lymphoid tissue (BALT) and the number of M. hyopneumoniae organisms (log) in the bronchoalveolar lavage (BAL) fluid1

Score T-lymphocytes (0-3)

Score B-lymphocytes (0-3)

Score macrophages2

(0-3)

Log of number of M. hyopneumoniae organisms in BAL fluid (log qPCR)2


Weeks PI

4

8

4

8

4

8

4

8


control

1.0 ± 0.0

0.0 ± 0.0

0.5 ± 0.5

0.5 ± 0.5

0.0 ± 0.0a, b

0.3 ± 0.2

-0.76 ± 0.21a

-0.69 ± 0.41a

nvLV

1.2 ± 0.2

0.5 ± 0.5

2.0 ± 0.5

0.8 ± 0.7

0.7 ± 0.5a, b

1.3 ± 0.8

1.25 ± 0.74a, b

2.41 ± 0.59b

nvHV

1.4 ± 0.2

1.2 ± 0.3

2.8 ± 0.2

1.6 ± 0.3

1.6 ± 0.9b

1.0 ± 0.4

3.44 ± 0.35b

1.89 ± 0.71a, b

vLV

0.8 ± 0.4

0.5 ± 0.2

1.4 ± 0.6

0.9 ± 0.2

0.0 ± 0.0a

0.1 ± 0.1

0.97 ± 0.53a, c

2.29 ± 0.39b

vHV

1.0 ± 0.3

1.0 ± 0.2

1.6 ± 0.4

1.5 ± 0.2

0.0 ± 0.0a

0.2 ± 0.1

1.96 ± 0.43b, c

1.80 ± 0.48b


nv non-vaccinated; v vaccinated; LV low virulent challenge strain; HV highly virulent challenge strain

1 Scoring was performed on samples of vaccinated and non-vaccinated pigs at 4 and 8 weeks after endotracheal inoculation with a low or highly virulent M. hyopneumoniae strain. A non-vaccinated and non- infected control group was also included.

2 Different lowercase letters correspond to significantly different values between the groups within a column

Vranckx et al. BMC Veterinary Research 2012 8:24   doi:10.1186/1746-6148-8-24

Open Data