Table 6

Age, body mass and selected laboratory parameters in relation to the outcome of therapy
Parameter Successfully treated Overdosed calves p value
(BE −5 to +5 mmol/l) (BE > +5 mmol/l)
n = 53 n = 55
On admission
 Age  (days) 10.0 (6.5/14.0) 8.0 (5.0/11.0) 0.046
 Body mass  (kg) 43.0 (38.8/48.7) 42.2 (38.2/47.6) 0.537
 Base excess  (mmol/l) −14.5 (−19.4/-5.1) −1.0 (−10.4/5.8) < 0.001
 HCO3-  (mmol/l) 15.8 (9.9/22.2) 25.5 (18.9/31.3) < 0.001
 Venous PCO2  (mm Hg) 47.3 (37.6/56.1) 56.4 (48.5/61.2) < 0.001
 D-lactate  (mmol/l) 5.0 (1.1/10.3) 0.8 (0.4/3.1) < 0.001
 L-lactate  (mmol/l) 1.3 (0.7/3.3) 2.7 (1.3/5.2) 0.002
 Anion gap  (mEq/l) 24.4 (20.4/27.9) 16.2 (12.0/27.5) 0.008
 Sodium  (mmol/l) 136.3 (130.8/140.3) 131.6 (129.1/135.4) 0.002
 Chloride  (mmol/l) 101.0 (95.0/107.0) 95.0 (88.0/98.0) < 0.001
 Potassium  (mmol/l) 4.8 (4.3/6.0) 5.2 (4.5/6.8) 0.153
 Ionized  Calcium  (mmol/l) 1.3 (1.2/1.3) 1.2 (1.1/1.3) 0.004
After 24 hours
 Base excess  (mmol/l) 1.5 (−0.8/3.8) 8.0 (6.4/10.3) < 0.001
 HCO3- (mmol/l) 27.6 (25.3/29.7) 34.4 (32.3/36.1) < 0.001
 Venous PCO2  (mm Hg) 53.2 (48.9/57.4) 59.9 (55.5/63.7) < 0.001
 D-lactate  (mmol/l) 2.1 (0.5/4.1) 0.4 (0.1/1.1) < 0.001
 L-lactate  (mmol/l) 1.3 (1.0/2.2) 1.5 (1.1/2.1) 0.747
 Anion gap  (mEq/l) 12.7 (10.0/14.8) 9.0 (6.6/11.6) < 0.001
 Sodium  (mmol/l) 135.0 (133.0/140.0) 135.9 (132.9/138.3) 0.768
 Chloride  (mmol/l) 101.0 (99.0/106.0) 97.0 (95.0/99.0) < 0.001
 Potassium  (mmol/l) 4.5 (4.2/4.9) 4.6 (4.2/4.9) 0.507
 Ionized  Calcium  (mmol/l) 1.2 (1.1/1.3) 1.2 (1.1/1.2) 0.283

Values are given as medians and 25-/75-quartiles.

Trefz et al.

Trefz et al. BMC Veterinary Research 2012 8:238   doi:10.1186/1746-6148-8-238

Open Data