Theoretical outcome of therapy of metabolic acidosis in 121 diarrheic calves based on previously published recommendations for the dosage of sodium bicarbonate . Positive values indicate calves that were theoretically overdosed, whereas negative values indicate calves that were theoretically underdosed (calculated with formula 3a). The intended amounts of sodium bicarbonate are based on posture/ability to stand, age and body mass of calves. For calves that would have received an oral rehydration solution, the buffer content of the recorded intake of ORS was used to calculate the theoretical success of therapy (an equivalent of 183 mmol of sodium bicarbonate was used for calves with expected treatment failure).
Trefz et al. BMC Veterinary Research 2012 8:238 doi:10.1186/1746-6148-8-238