Regions around the SERCA1 mutations. Multiple sequence alignment of the SERCA1 protein in the region of the three different mutations demonstrates the conservation of residues across vertebrates. In addition, the mutant residues are conserved in all known bovine SERCA1 paralogs.
Murgiano et al. BMC Veterinary Research 2012 8:186 doi:10.1186/1746-6148-8-186