Table 4

Genes involved in over-manfested cellular pathways in canine mammary cancer cells grown as a co-culture with macrophages

Pathway

number of genes

P-value


Inflammation mediated by chemokine and cytokine signaling pathway

21

1.81E-11


Toll receptor signaling pathway

7

9.44E-06


B cell activation

7

6.80E-05


Purine metabolism

3

1.04E-04


T cell activation

8

1.60E-04


Acetate utilization

2

6.87E-04


Apoptosis signaling pathway

6

3.86E-03


Adenine and hypoxanthine salvage pathway

2

8.65E-03


Interleukin signaling pathway

6

8.68E-03


Plasminogen activating cascade

2

1.19E-02


5-Hydroxytryptamine degredation

2

2.19E-02


Lysine biosynthesis

1

2.48E-02


Salvage pyrimidine deoxyribonucleotides

1

3.69E-02


PDGF signaling pathway

5

3.99E-02


Methylcitrate cycle

1

4.89E-02


The list of over-manifested cellular PANTHER pathways in cancer cells grown as co-cultures with macrophages. The binomial test for each PANTHER pathway was used

Król et al. BMC Veterinary Research 2012 8:16   doi:10.1186/1746-6148-8-16

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