Table 1
Functional GO categories and KEGG pathways enriched with genes that were differentially expressed in response to a combination of PPC and saponins
GO categories and KEGG pathways Features* p-value†
Inflammatory response 26/236 <0.001
Complement and coagulation cascade 10/92 0.026
Antigen processing and presentation 9/77 0.022
Chemokine activity 5/6 <0.001
Valine, leucine and isoleucine degradation 17/79 <0.001
Arginine and proline metabolism 14/107 <0.001
Tryptophan metabolism 12/60 <0.001
Tyrosine metabolism 10/51 <0.001
Glycine, serine and threonine metabolism 10/56 <0.001
Lysine degradation 8/57 0.009
Beta-alanine metabolism 6/41 0.022
Lipid metabolic process 27/300 0.004
Retinol metabolism 18/79 <0.001
Fatty acid metabolic process 14/97 <0.001
Glycerolipid metabolism 13/68 <0.001
C21-steroid hormone metabolism 8/49 0.002
Sphingolipid metabolism 7/51 0.018
Carbohydrate metabolic process 22/264 0.023
Mitochondrion 78/1091 0.002
Lysosome 20/183 <0.001
Protein folding 19/180 0.002
Peroxisome 16/118 <0.001
Cell surface 15/136 0.004
Metabolism of xenobiotics 12/55 <0.001
Glutathione metabolism 12/69 <0.001
Glycosaminoglycan degradation 5/32 0.031
Extracellular space 28/367 0.032
Basement membrane 9/68 0.008
Hormone activity 8/41 <0.001
Digestion 7/49 0.014

* Numbers of genes among DEG and on the microarray platform.

† Yates’ corrected chi-square.

Kortner et al. BMC Veterinary Research 2012 8:101   doi:10.1186/1746-6148-8-101

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