Table 1

Clinical signs and laboratory results for dogs in the AP protocol group and the P protocol group at time of diagnosis

Azathioprine- Prednisolone Protocol

Prednisolone Protocol


Clinical signs

Present

Absent

na

Present

Absent

n

Pb


Anorexia

119

30

149

55

17

72

0.554

Vomiting

44

105

149

27

46

73

0.263

Diarrhea

23

126

149

17

56

73

0.153

Dyspnea

16

133

149

4

69

73

0.199

Fever

69

80

149

33

38

72

0.981

Pale mucous membranes

146

3

149

72

1

73

0.735

Icterus

57

92

149

27

46

73

0.855

Petechiae

8

141

149

1

72

73

0.156

Red urine

47

102

149

17

55

72

0.223


Laboratory results

Median

Range

n

Reference

Median

Range

n


Hematocrit (%)

13

0.04-0.27

149

42-57

12

0.05-0.26

73

0.36

Reticulocytes (%)

8

0.1-90

147

< 2

5.8

0.1-51.5

64

0.29

Corrected reticulocytes (%)

2.7

0.01-19.2

147

< 2

2

0.02-14.3

64

0.11

Osmotic red cell fragility (mOsm/L)

238

120-317

139

< 162

250

131-317

28

0.28

Leukocytes (x109/L)

27.9

2.1-130

148

5.9-13.8

21.7

5.7-78.6

68

0.3

Band neutrophils (x109/L)

1.4

0-22.1

148

0-0.3

1

0-21.9

67

0.08

Urea (mmol/L)

7.6

2.9-69.5

123

3.0-12.5

7.4

2.3-49.5

45

0.8

Creatinine (μmol/L)

41.8

0.4-652

112

< 50

41.2

6.5-228.4

48

0.16

PTc (seconds)

8

6-12

98

7 ± 1

7

7-10

13

0.74

APTTd (seconds)

19.8

11-98

98

14 ± 1

17.4

9.1-64.8

37

0.98

Fibrinogen (g/L)

3.9

0.6-13.8

96

2-5

5

2.3-8.2

13

0.11

Thrombocytes (x109/L)

122

0-958

140

150-400

230

9-1079

65

0.00001*

Duration of clinical signs (days)

6

0-141

149

3

0-131

73

0.015*


a Number of dogs in which the parameter was determined.

b P = P value

c PT = Prothrombin time

d APTT = Activated partial thromboplastin time

Piek et al. BMC Veterinary Research 2011 7:15   doi:10.1186/1746-6148-7-15

Open Data