Figure 6.

Alignment of amino acid sequences in the highly polymorphic region (HPR) of the HE genes of various strains of ISAV (modified from Kibenge et al. [19]). The amino acid sequence corresponding to the HE-HPR of the Chilean ISAV in this disease outbreak is highlighted in yellow, and identifies it as HPR7. Sequences that are not determined are indicated by dots, and amino acid (aa) deletions in the HPR are indicated by dashes. The HPR groups identified are as reported by Nylund et al. [23] and Plarre et al. [24]; other sources of information are indicated as *Markussen et al. [20], **Cunningham et al. [25], ***Cook-Versloot et al. [26], and ****Mjaaland et al. [27].