Table 2

Segregation analysis – Parameter estimates, log-likelihood and AIC associated with the general autosomal mode of transmission and the general, dominant and recessive X-linked modes of transmission.

Autosomal

X-linked


General

General

Dominant

Recessive


q2

0.39

0.39

0.54

0.46

f11

0.38

0.29

1

0

f12

0.31

0

0

= f11

f22

0.41

0.88

= f12

1

No.

4

3

1

1

-2 lnL

102.6

82.4

87

87

AIC

110.6

88.4

89

89

χ2(df)

4.6(2)

4.6(2)

P

0.10

0.10


q2: frequency of the risk allele 2; f11, f12, f22: penetrances of genotypes 11, 12 and 22. No.: No. of independent parameters estimated = (no. of parameters in the model)-(no. of parameters that converged to a boundary); lnL: log-likelihood; AIC: Aikaike criterion (-2 lnL + 2 No). χ2 (df): chi-squared test comparing the general X-linked model with the restricted X-linked models. P: associated p-value.

Vilboux et al. BMC Veterinary Research 2008 4:10   doi:10.1186/1746-6148-4-10

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