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Coat colour in dogs: identification of the Merle locus in the Australian shepherd breed

Benoit Hédan1, Sébastien Corre1, Christophe Hitte1, Stéphane Dréano1, Thierry Vilboux1, Thomas Derrien1, Bernard Denis2, Francis Galibert1, Marie-Dominique Galibert1 and Catherine André1*

Author Affiliations

1 UMR 6061 CNRS, Génétique et Développement, Faculté de Médecine, Université de Rennes1, 35043 RENNES Cédex, France.

2 5 avenue Foch 54200 Toul, France.

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BMC Veterinary Research 2006, 2:9  doi:10.1186/1746-6148-2-9

Published: 27 February 2006

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Additional File 1:

Characteristics of the markers used in the genetic linkage studies. a CFA : Canis familiaris chromosome.b Starred markers were selected from the CanFam 1.0 canine sequence draft, c marker corresponding to marker FH2537 from Guyon et al. [13], d number of alleles as determined from the sub-pedigree. E Markers flanking SOX10 gene.

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Additional File 2:

Scheme of two-point linkage analysis of the merle phenotype in the Australian Shepherd dog pedigrees on CFA10. Two-point linkage analysis of the merle phenotype in the Australian shepherd dog sub-pedigree (in black) and complete pedigree (in brown) (Lod scores at theta = 0) is shown on the right. An ordered list of genotyped markers (right) and genes (left) and their position in Mb are indicated in the middle. An ideogram of the canine chromosome 10 is shown on the left with the corresponding human chromosomal conserved segments. NB: genomic sequence systematically starts at an arbitrary coordinate of 3 Mb to include the non-sequenced centromeric region.

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