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Effect of metoclopramide on open-field activity and tonic immobility test in chicks |
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| Metoclopramide (mg/kg, subcutaneously) |
Squares crossed/5 minutes |
Duration of immobility (second) |
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|
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| 0 (saline-control) |
3.5 ± 1.4 |
10.5 ± 2.7 |
| 5 |
1.0 ± 1.0* |
54.9 ± 18.1 |
| 10 |
0.1 ± 0.1* |
130.6 ± 26.3*† |
|
Open-field activity was measured 20 min after drug administration. Tonic immobility test was done immediately after the open-field test. Values are mean ± SE of 8 chicks/group. * Significantly different from the respective control values, P < 0.05. † Significantly different from the 5 mg/kg treatment group, P < 0.05. | ||
Al-Zubaidy and Mohammad BMC Veterinary Research 2005 1:6 doi:10.1186/1746-6148-1-6 |
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