MIA is expressed in NF1 tumors. Immunohistochemical detection of MIA on paraffin sections of NF1-associated tumors. Melanoma samples were used as positive controls. MIA is expressed in each type of the analysed NF1 tumors. Malignant peripheral nerve sheath tumours (MPNSTs) have higher cellular density, yielding more MIA-positive cells per visual field.
Kolanczyk et al. BMC Medicine 2011 9:82 doi:10.1186/1741-7015-9-82