Table 1

Reporting of aspects of trial design, conduct and analysis: Stratified by diseases and types of Intervention

Interventions

All

Drug

COPD

Heart failure

Diabetes

Stroke


Non-drug

Drug

Non-drug

Drug

Non-drug

Drug

Non-drug

Drug

Non-drug


Number of trials

161

70

91

20

29

12

19

26

22

12

21

Reporting of between- group comparisons, % (n)

90% (145)

90% (63)

89% (81)

100% (20)

93% (27)

67% (8)

95% (18)

92% (24)

82% (18)

92% (11)

86% (18)

Primary outcome, % (n)

33% (53)

50% (35)

20% (18)

70% (14)

7% (2)

17% (2)

21% (4)

42% (11)

36% (8)

67% (8)

19% (4)

Primary outcome is only one measure, % (n)

21% (34)

31% (22)

13% (12)

35% (7)

0% (0)

8% (1)

16% (3)

27% (7)

32% (7)

58% (7)

10% (2)

No statistical comparison of baseline characteristics, % (n)

68% (110)

79% (55)

60% (55)

85% (17)

59% (17)

83% (10)

68% (13)

73% (19)

73% (16)

75% (9)

43% (9)

Reporting of handling of missing data, % (n)

17% (28)

21% (15)

13% (12)

20% (4)

10% (3)

8% (1)

5% (1)

27% (7)

9% (2)

25% (3)

33% (7)

Intention-to-treat analysis reported, % (n)

42% (67)

53% (37)

33% (30)

70% (14)%

24% (7)

33% (4)

26% (5)

46% (12)

27% (6)

58% (7)

57% (12)

Reporting of P values and 95% CI % (n)

24% (38)

31% (22)

20% (18)

45% (9)

24% (7)

8% (1)

16% (3)

19% (5)

32% (7)

58% (7)

5% (1)


Vollenweider et al. BMC Medicine 2011 9:73   doi:10.1186/1741-7015-9-73

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