Table 2

Examples of imaging techniques used in the past and that can be used in the future

Assessments

Previous functional

imaging protocols

Optimized functional

imaging protocols


DA-rich graft survival and growth

18F-DOPA PET

18F-DOPA PET

Patient selection

-

18F-DOPA PET

DA release from the graft

11C-raclopride with challenge

11C-raclopride with challenge

Graft-derived 5-HT innervation and growth

-

11C-DASB

Graft-induced dyskinesias

-

11C-DASB PET/18F-DOPA PET ratio

11C-DASB PET/123I-FP-CIT SPECT ratio

Inflammatory and immune responses around the graft

-

11C-PK11195

Brain activation during movement

H215O PET with motor execution tasks

fMRI with motor execution tasks

Functional connectivity between brain regions

-

Resting-state fMRI

White matter structural connectivity

-

Diffusion Tensor Imaging


Politis BMC Medicine 2011 9:50   doi:10.1186/1741-7015-9-50

Open Data