Table 1 |
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Clinical and laboratory characteristics of the study subjectsa |
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|
Characteristics |
DC |
CD |
GS |
|
|
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|
Number of samples |
39 |
42 |
26 |
|
Age at diagnosis, yr (mean ± SD) |
33.36 ± 10.94 |
26.88 ± 11.77 |
30.73 ± 12.19 |
|
Sex (F/M) |
23/16 |
32/10 |
17/9 |
|
Intestinal symptoms |
Dyspepsia |
Chronic diarrhea Abdominal pain Weight fluctuation Weakness Smelly, fatty stools |
Diarrhea Abdominal pain Weight loss Gas |
|
Extraintestinal symptoms |
None |
Bone or joint pain Osteoporosis Behavioral changes Tingling leg numbness Muscle cramps Missed menstruation Infertility Recurrent miscarriage Delayed growth Thyroiditis Tooth discoloration Unexplained anemia |
Bone or joint pain Osteoporosis Leg numbness Muscle cramps Unexplained anemia Glossitis |
|
EMA-IgA |
All negative |
34 positive 3 negative 5 not determined |
All negative |
|
tTG-IgA |
All negative |
37 positive 5 negative |
All negative |
|
AGA-IgA/IgG |
All negative |
29 positive 10 negative 3 not determined |
12 positive 13 negative 1 not determined |
|
MHC profile |
None determined |
22 DQ2 and/or DQ8 positive 2 DQ2 and/or DQ8 negative 18 not determined |
12 DQ2 and/or DQ8 positive 9 DQ2 and/or DQ8 negative 5 not determined |
|
Wheat IgE |
1 positive 37 negative 1 not determined |
18 negative 24 not determined |
22 negative 4 not determined |
|
|
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aDC, dyspeptic controls; CD, celiac disease; GS, gluten-sensitive individuals; SD, standard deviation; EMA-IgA, endomysium antibodies-immunoglobulin A; tTG-IgA, tissue transglutaminase-immunoglobulin A; AGA-IgA/IgG, anti-gliadin antibodies-immunoglobulin A/immunoglobulin G; MHC, major histocompatibility complex; IgE, immunoglobulin E. |
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Sapone et al. BMC Medicine 2011 9:23 doi:10.1186/1741-7015-9-23 |
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