Table 2

Spearman correlation coefficients, P values, and false discovery rate-corrected Q values between venous hemodynamic insufficiency severity score and perfusion-weighted measures in relapsing-remitting patients

Mean transit time,

r, P/Q

Cerebral blood flow,

r, P/Q

Cerebral blood volume,

r, P/Q


Gray matter

0.52,a 0.039/0.100a

-0.70,b 0.002/0.022b

-0.58,a 0.019/0.062a

White matter

0.53,a 0.034/0.094a

-0.71,b 0.002/0.022b

-0.49, 0.054/0.110

Caudate

0.50,a 0.049/0.110a

-0.38, 0.142/0.189

-0.30, 0.266/0.319

Putamen

0.47, 0.065/0.117

-0.72,b 0.002/0.022b

-0.42, 0.107/0.161

Globus pallidus

0.44, 0.087/0.142

-0.69,b 0.003/0.022b

-0.22, 0.404/0.428

Thalamus

0.46, 0.074/0.127

-0.65,b 0.007/0.042b

-0.62,a 0.011/0.052a

Pulvinar thalamus

0.25, 0.342/0.385

-0.67,b 0.003/0.022b

-0.50, 0.051/0.110

Hippocampus

0.34, 0.201/0.250

-0.61,a 0.012/0.052a

-0.41, 0.117/0.162

Amygdala

0.14, 0.604/0.604

-0.4, 0.091/0.142

-0.47, 0.064/0.117

Nucleus accumbens

0.49, 0.055/0.110

-0.60a 0.015/0.054a

-0.26, 0.336/0.384

Red nucleus

0.37, 0.163/0.210

-0.56,b 0.025/0.075b

-0.41, 0.112/0.161

Substantia nigra

0.17, 0.539/0.554

-0.60,a 0.013/0.052a

-0.23, 0.394/0.428


aFindings significant without false discovery rate (FDR) correction; bsignificant correlations and findings surviving FDR correction.

Zamboni et al. BMC Medicine 2011 9:22   doi:10.1186/1741-7015-9-22

Open Data