Process-based pathogenesis of ALI. Traditional causes of or risk factors for ALI maybe contributed to in certain patients by hospital-acquired harm (red) and modified in their potency for causing ALI by multiple patient's susceptibility (blue). Depending on the balance of these factors the processes that determine the natural history of ALI are initiated in the lung.
Proudfoot et al. BMC Medicine 2011 9:132 doi:10.1186/1741-7015-9-132