Table 3

Goals to improve gradually closed-loop performance

Factor

Desirable improvements


Insulin delivery

Faster absorption

Glucose sensing

Increased accuracy and reliability; reduced false-positive hypoglycemia alarms

Insulin modulation

Adaptive algorithms

Dual-hormone systems

Dual-chamber pumps

Communication between glucose sensor and insulin pump

More reliable connectivity; standardized communication protocol

Human factors

Reduced size of devices; enhanced ease of use; sensing and delivery from a single body port


Elleri et al. BMC Medicine 2011 9:120   doi:10.1186/1741-7015-9-120

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