Table 1

The genotype and allele frequencies of MNS16A in patients with nasopharyngeal carcinoma and cancer-free controls

MNS16Aa

Cases, n (%), n = 798b

Controls, n (%), n = 1019b

OR (95% CI)c,d

Pc


Alleles, bp

302 (reference)

1520 (95. 2)

1903 (93. 4)

1. 00

243

44 (2. 8)

76 (3. 7)

0. 74 (0. 51 to 1. 08)

0. 12

272

31 (1. 9)

59 (2. 9)

0. 65 (0. 42 to 1. 01)

0. 058

333

1 (0. 06)

0

-

-

Genotypes

302/302 (reference)

724 (90. 7)

891 (87. 4)

1. 00

243/302

41 (5. 2)

65 (6. 4)

0. 80 (0. 53 to 1. 20)

0. 29

272/302

30 (3. 8)

56 (5. 5)

0. 64 (0. 41 to 1. 01)

0. 059

243/243

1 (0. 1)

4 (0. 4)

0. 36 (0. 04 to 3. 73)

0. 41

243/272

1 (0. 1)

3 (0. 3)

0. 33 (0. 04 to 2. 94)

0. 32

302/333

1 (0. 1)

0

-

-

Group of genotypes

LL (reference)

725 (90. 9)

891 (87. 4)

1. 00

SL

71 (8. 9)

121 (11. 9)

0. 73 (0. 53 to 0. 99)

0. 037

SS

2 (0. 2)

7 (0. 7)

0. 35 (0. 07 to 1. 69)

0. 17

SL + SS

73 (9. 1)

128 (12. 6)

0. 71 (0. 52 to 0. 96)

0. 025

Group of alleles

L (reference)

1521 (95. 0)

1903 (93. 0)

1. 00

S

75 (5. 0)

135 (7. 0)

0. 86 (0. 78 to 0. 96)

0. 014


aOwing to genotyping failure, the actual sample size was 798 and 1019 for the cases and controls, respectively.

bL allele was 302 or 333 bp; S allele was 243 or 272 bp.

cThe odds ratios (ORs) and P values were adjusted for age, gender, tobacco and alcohol use, smoking level, ethnicity and family history.

dConfidence interval.

Zhang et al. BMC Medicine 2011 9:106   doi:10.1186/1741-7015-9-106

Open Data