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Open Access Research article

How large are the nonspecific effects of acupuncture? A meta-analysis of randomized controlled trials

Klaus Linde1*, Karin Niemann1, Antonius Schneider1 and Karin Meissner12

Author Affiliations

1 Institute of General Practice, Technische Universität München, Orleansstrasse 47, D-81667 Munich, Germany

2 Institute of Medical Psychology, Ludwig-Maximilians-University, Goethestrasse 31, D-80336 Munich, Germany

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BMC Medicine 2010, 8:75  doi:10.1186/1741-7015-8-75

Published: 23 November 2010

Additional files

Additional file 1:

Search strategy MEDLINE 19 April 2010 (1966-2010, week 15). Search strategy. Embase search, 19 April 2010 (1988-2010, week 15). Table S1. Additional publications related to included studies. Table S2. Excluded studies. Table S3. Subgroup and sensitivity analyses. Figure S1. The "specific" effect of acupuncture (difference between groups receiving acupuncture and sham acupuncture). Figure S2. Funnel plot of studies comparing acupuncture versus sham acupuncture. Figure S3. The "total" effect of acupuncture (difference between groups receiving acupuncture and no acupuncture). Figure S4. Funnel plot of studies comparing acupuncture versus no acupuncture.

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