Open Access Highly Accessed Research article

Chest compressions before defibrillation for out-of-hospital cardiac arrest: A meta-analysis of randomized controlled clinical trials

Pascal Meier12*, Paul Baker3, Daniel Jost4, Ian Jacobs5, Bettina Henzi6, Guido Knapp7 and Comilla Sasson8

Author Affiliations

1 University of Michigan Medical Center, Cardiovascular Medicine, Ann Arbor, Michigan, USA

2 VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA

3 SA Ambulance Service, Eastwood, South Australia, Australia

4 Service Medical d'Urgence, Brigade de Sapeurs-Pompiers Paris, Paris, France

5 Discipline of Emergency Medicine, University of Western Australia, Crawley, Australia

6 Department of Clinical Research, University of Bern Medical School, Bern, Switzerland

7 Department of Statistics, TU Dortmund University, Germany

8 Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA

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BMC Medicine 2010, 8:52  doi:10.1186/1741-7015-8-52

Published: 9 September 2010

Additional files

Additional file 1:

Supplementary table 1. PRISMA statement checklist.

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Additional file 2:

Supplementary table 2. Detailed literature search strategy with search terms used for Medline.

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Additional file 3:

Supplementary figure 1. Meta-regression plot. Meta-regression plot of odds ratios (OR) versus response interval (seconds). Size of circles indicate study weights in a mixed-effects model.

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Additional file 4:

Supplementary table 6. Predicted odds ratios for variable response intervals.

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Additional file 5:

Supplementary tables 3 - 5. Sensitivity analyses with different meta-analytical approaches.

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