Table 3

Recommended procedure for substitution of vitamins during total parenteral nutrition (personal communication Ramsauer and Vetter, Berlin, Germany).

Parenteral nutrition via peripheral venous access


Main infusion

Adjuvants (daily dose)

Speed of operation


500 mL glucose-infusion 5%

• 200 mg vitamin B1 (thiaminchloride),

• 200 mg vitamin B6 (pyridoxine),

• 200 μg vitamin B12 (cyanocobalamine),

• 2000 mg vitamin C (ascorbic acid)

50 mL/h


Parenteral nutrition via central venous access


Main infusion

Adjuvants (daily dose)

Speed of operation


500 mL glucose-infusion 40%

• 200 mg vitamin B1(thiaminchloride),

• 200 mg vitamin B6 (pyridoxine),

• 200 μg vitamin B12 (cyanocobalamine),

• 2000 mg vitamin C (ascorbic acid)

50 mL/h


Jueckstock et al. BMC Medicine 2010 8:46   doi:10.1186/1741-7015-8-46

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