Network analysis of the top 250 predictor genes. Ingenuity Pathway Analysis was applied to the top 250 predictor genes to identify gene networks based on connectivity (red: predictor of sensitivity, green: predictor of resistance). The top two networks are shown here. The network scores for networks 1 and 2 are 54 and 49, respectively. Nodes are displayed using shapes that represent the functional class of the gene product. Edges are displayed with labels that describe the nature of the relationship between the nodes. All edges are supported by at least 1 reference from the literature, or from canonical information stored in the Ingenuity Pathways Knowledge Base.
Kuo et al. BMC Medicine 2009 7:77 doi:10.1186/1741-7015-7-77