Table 2

OXTR promoter CpG methylation levels in peripheral blood mononuclear cells

Site

AutD cases (95% CI), (n = 20)

Controls (95% CI), (n = 20)

t Test


-860

35.1% (22.6 to 46.7)

12.2% (6.5 to 17.9)

0.0009

-901

52.0% (42.4 to 61.6)

45.2% (32.5 to 57.8)

0.3761

-924

68.1% (58.2 to 78.0)

65.8% (54.4 to 77.3)

0.7558

-934

56.4% (43.4 to 69.4)

33.4% (22.2 to 44.6)

0.0081

-959

50.9% (42.4 to 59.4)

32.0% (23.2 to 40.8)

0.0026


Bold text indicates a significant result by Satterthwaite test; % = percentage methylated.

CI = confidence interval; AutD = autism disorder.

Gregory et al. BMC Medicine 2009 7:62   doi:10.1186/1741-7015-7-62

Open Data