Table 1

Description of clinical details associated with the temporal cortex tissue used in the methylation and expression analyses

Case no.

Sex

Age (years)

PMI (h)

Diagnosis

Cause of death


Controls:

UMB-1185*

M

4

17

Control

Drowning

UMB-1860*

M

8

5

Control

Cardiac arrhythmia

B-3829*

M

22

24

Control

Central hepatic laceration

UMB-1706*

F

8

20

Control

Rejection of heart transplant

UMB-1377

F

5

20

Control

Drowning

B-6207

M

16

26

Control

Ischemic heart attack

B-6221

M

22

24

Control

Unknown

B-5873

M

28

23

Control

Unknown

B-4211

M

30

23

Control

Cardiac arrhythmia

Autism:

B-5569*

M

5

25.5

PDD-NOS

Drowning

UMB-4721*

M

8

16

Autism

Drowning

B-5144*

M

20

23.7

Autism

Traffic accident

UMB-4671*

F

4

13

Autism

Accident

UMB-1174

F

7

14

Autism

Sudden death, seizure

B-6294

M

16

Unknown

Autism

Unknown

B-6337

M

22

25

Autism

Choking

B-5000

M

27

8.3

Autism

Drowning

B-5173

M

30

20

Autism

Gastrointestinal hemorrhage


Paired samples for expression analysis are denoted by an asterisk. Italicized samples were excluded from the methylation analysis to maintain phenotypic homogeneity.

PMI = postmortem interval; PDD-NOS = Pervasive Developmental Disorder Not Otherwise Specified.

Gregory et al. BMC Medicine 2009 7:62   doi:10.1186/1741-7015-7-62

Open Data