Figure 1.

Graphical representation of the 0.7 Mb heterozygous deletion in 3p25.3 (8,231,927-8,985,513 base pairs) within an individual with autism identified by array comparative genomic hybridization (CGH). The horizontal ideogram represents the chromosome 3 region of interest with the log2 plot below it of array CGH results from the tilepath clones (individual blue circles) on the genomic array. The dotted line at '0' represents copy neutral log2 plot between the cohybridized samples, while the green line represents single copy gain and the red line single copy loss. OXTR and four adjacent genes are contained within a deletion called in Nexus by circular binary segmentation (CBS) [40] (bold black line). Known copy number variants from the Database of Genomic Variants http://projects.tcag.ca/variation/ webcite are denoted by horizontal pink bars.

Gregory et al. BMC Medicine 2009 7:62   doi:10.1186/1741-7015-7-62
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