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Univariate associations between molecular markers and advanced prostate cancer at the time of diagnosis. Advanced cancer was defined as skeletal metastases or clinical stage ≥ T3. Predictive accuracy of each marker is given as AUC. To facilitate comparisons between markers, the odds ratios are for an increase of one-quarter of a standard deviation. |
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| Marker |
Odds ratio |
95% CI |
AUC |
|
|
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| Total PSA |
3.19 |
2.38, 4.27 |
0.791 |
| Free PSA |
3.06 |
2.30, 4.08 |
0.776 |
| Complexed PSA |
3.11 |
2.33, 4.16 |
0.793 |
| Percent free to total PSA |
0.85 |
0.80, 0.90 |
0.641 |
| Human kallikrein 2 |
1.25 |
1.13, 1.38 |
0.604 |
Ulmert et al. BMC Medicine 2008 6:6 doi:10.1186/1741-7015-6-6 |
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