Table 2

Distribution of valvular regurgitation at initial echocardiogram in 918 men exposed to fenfluramine and/or dexfenfluramine

Ages

<20 (n = 12)

20–29 (n = 31)

30–39 (n = 125)

40–49 (n = 249)

50–59 (n = 281)

60–69 (n = 166)

70+ (n = 54)

All ages (n = 918)


Aortic regurgitation

None (%)

91.7

90.3

86.4

79.5

73.7

62.0

55.6

74.6

Trace (%)

8.3

9.7

10.4

13.6

12.8

24.1

27.8

15.5

Mild (%)

0

0

2.4

4.8

12.1

8.4

13.0

7.6

moderate (%)

0

0

0.80

2.0

1.4

4.2

3.7

2.1

severe (%)

0

0

0

0

0

1.2

0

0.22

Mitral regurgitation

none (%)

58.3

58.1

48.0

44.2

35.9

34.9

44.4

41.2

trace (%)

33.3

35.5

48.0

48.6

54.4

47.6

46.3

49.4

Mild (%)

8.3

3.2

4.0

7.2

7.5

9.6

5.6

7.1

moderate (%)

0

0

0

0

1.1

6.0

3.7

1.6

severe (%)

0

3.2

0

0

1.1

1.8

0

0.76

Tricuspid regurgitation

none (%)

41.7

38.7

37.6

34.1

31.7

26.5

31.5

32.5

trace (%)

33.3

51.6

60.0

56.6

62.6

59.6

55.6

59.0

Mild (%)

16.7

9.7

2.4

7.2

4.3

9.0

9.3

6.3

moderate (%)

0

0

0

2.0

0.71

4.2

3.7

1.7

severe (%)

8.3

0

0

0

0.71

0.60

0

0.44


Dahl et al. BMC Medicine 2008 6:34   doi:10.1186/1741-7015-6-34

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