Table 3

The age and sex adjusted and multivariate adjusted association of the SNPs with incident CHD


Participants (cases)
Age and sex adjusted
Multivariate adjusted *

rs10757274



     AA
1834 (184)
Reference
Reference
     AG
3107 (273)
0.89 (0.74, 1.07)
0.90 (0.74, 1.09)
     GG
1310 (131)
1.00 (0.80, 1.26)
0.99 (0.78, 1.25)




rs10757278



     AA
1909 (188)
Reference
Reference
     AG
3097 (269)
0.90 (0.74, 1.08)
0.90 (0.74, 1.09)
     GG
1264 (127)
1.01 (0.81, 1.27)
1.00 (0.79, 1.26)

* adjusted for age, sex, BMI, serum total and HDL cholesterol, smoking, diabetes, systolic and diastolic blood pressure.

CI = Confidence interval, CHD = Coronary heart disease, MI = Myocardial infarction

Dehghan et al. BMC Medicine 2008 6:30   doi:10.1186/1741-7015-6-30