|
The age and sex adjusted and multivariate adjusted association of the SNPs with incident CHD and MI |
||||||
| Allele |
All participants |
Incident cases |
Age and sex adjusted |
Multivariate adjusted HR* |
||
|
|
||||||
| CHD |
rs10757274 |
G |
45.8 |
45.5 |
1.03 (0.90, 1.18) |
1.00 (0.87, 1.15) |
| rs10757278 |
G |
44.9 |
42.7 |
1.03 (0.90, 1.18) |
1.00 (0.87, 1.15) |
|
| MI |
rs10757274 |
G |
45.8 |
43.8 |
0.94 (0.82, 1.08) |
0.97 (0.84, 1.11) |
| rs10757278 |
G |
44.9 |
42.7 |
0.93 (0.81, 1.06) |
0.95 (0.83, 1.10) |
|
|
* adjusted for age, sex, BMI, serum total and HDL cholesterol, smoking, diabetes, systolic and diastolic blood pressure. CI = Confidence interval, CHD = Coronary heart disease, MI = Myocardial infarction | ||||||
Dehghan et al. BMC Medicine 2008 6:30 doi:10.1186/1741-7015-6-30 |
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