Clinical characterization and the mutation spectrum in Swedish adenomatous polyposis families

Gunilla Kanter-Smoler¹^,5 , Kaisa Fritzell² , Anna Rohlin¹ , Yvonne Engwall¹ , Birgitta Hallberg¹ , Annika Bergman¹ , Johan Meuller¹^,6 , Henrik Grönberg³ , Per Karlsson⁴ , Jan Björk² and Margareta Nordling¹

¹Department of Molecular and Clinical Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

²The Swedish Polyposis Registry, Department of Medicine, Karolinska Institute, Stockholm, Sweden

³Department of Medical Epidemiology and Biostatistics Karolinska Institutet, Stockholm, Sweden

⁴Department of Oncology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

⁵AstraZeneca R&D Mölndal, ATCG, HE 351, Mölndal, Sweden

⁶AstraZeneca R&D Mölndal, Structural Chemistry Laboratory, SC425, Mölndal, Sweden

author email corresponding author email

BMC Medicine 2008, 6:10doi:10.1186/1741-7015-6-10


Published:	24 April 2008

Additional files

Additional file 1:

Clinical characterization of mutation-positive data. A compilation of all of the clinical data of the APC gene mutation carriers.

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Additional file 2:

Pathogenic mutations detected in the APC gene. Description of all mutations and the molecular genetic consequence of each mutation [52-66].

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