Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

doi:10.1186/1741-7015-5-22

BMC Medicine

Volume 5

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Briollais L
Wang Y
Rajendram I
Onay V
Shi E
Knight J
Ozcelik H

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Wang Y
Rajendram I
Onay V
Shi E
Knight J
Ozcelik H
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Research article

Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

Laurent Briollais¹^,2 , Yuanyuan Wang¹ , Isaac Rajendram¹^,3 , Venus Onay¹^,3^,4 , Ellen Shi⁵ , Julia Knight¹^,2 and Hilmi Ozcelik³^,4^,5

¹Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, M5T 3L9, Canada

²Public Health Sciences Department, University of Toronto, Toronto, M5T 3M7, Canada

³Fred A Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, M5T 3L9, Canada

⁴Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, M5G 1X5, Canada

⁵Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, M5G 2L9, Canada

author email corresponding author email

BMC Medicine 2007, 5:22doi:10.1186/1741-7015-5-22


Published:	7 August 2007

Additional files

Additional file 1:

Positions of primers and probes used in the study in their appropriate accession numbers. Positions of primers and probes used in the study in their appropriate accession numbers.

Format: XLS Size: 23KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

Optimal MgCl₂concentrations and annealing temperatures for each SNP PCR. Optimal MgCl₂concentrations and annealing temperatures for each SNP PCR.

Format: XLS Size: 17KB Download file

This file can be viewed with: Microsoft Excel Viewer