Table 1

Predictive statistics for schizophrenia using all 65 subjects.

Region

False+, False-

PPV%

NPV%

Likelihood ratio +

Likelihood ratio -

Sensitivity %

Specificity %

Effect size


Right cerebellum

7, 6

22

89

2.04

0.86

25

88

-0.82

Left uncus

4, 7

20

88

1.78

0.94

13

93

-0.33

Left inferior temporal gyrus

2, 5

60

92

10.69

0.65

38

96

-0.68


Statistics for the prediction of the development of schizophrenia within a 10-year period, based on changes in grey matter in the right cerebellum, left uncus and left inferior temporal gyrus (n = 65, all familial high-risk subjects with two scans in the first 4 years of the Edinburgh High Risk Study).

+ positive; - negative; NPV negative predictive value; PPV positive predictive value

Job et al. BMC Medicine 2006 4:29   doi:10.1186/1741-7015-4-29

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