Table 1

Demographic and clinical characteristics at baseline for patients with a major depressive episode (full analysis set)

Characteristic

WS® 5570 600 mg/day N = 119

WS® 5570 1200 mg/day N = 124

Placebo N = 81

p-value


Sex:

0.13*

Female

n (%)

67 (56.3)

82 (66.1)

56 (69.1)

Male

n (%)

52 (43.7)

42 (33.9)

25 (30.9)

Age (years)

Mean ± SD

46.3 ± 11.5

46.1 ± 10.7

46.9 ± 11.8

0.69§

HAM-D total score

Mean ± SD

22.8 ± 3.3

22.6 ± 3.8

23.6 ± 4.2

0.31

CGI severity of illness:

0.20*

Mildly or moderately ill

n (%)

67 (56.3)

62 (50.0)

46 (56.8)

Markedly or severely ill

n (%)

52 (43.7)

62 (50.0)

35 (43.2)

MADRS

Mean ± SD

27.2 ± 5.5

26.3 ± 6.0

28.0 ± 6.2

0.09§

BDI

Mean ± SD

23.2 ± 7.9

23.3 ± 8.0

25.7 ± 8.9

0.05§

SF-36 summary measure mental health

Mean ± SD

25.1 ± 11.7

27.7 ± 13.3

23.7 ± 11.1

0.16§


For the HAM-D, MADRS and BDI, a higher value indicates more severe impairment whereas for the SF-36, a lower score indicates more severe impairment.

*Two-sided chi-square test

§Two-sided Kruskal-Wallis test

Kasper et al. BMC Medicine 2006 4:14   doi:10.1186/1741-7015-4-14

Open Data