Table 3

Baseline characteristics of patients who discontinued due to poor response or symptom worsening

Characteristic

Study 1 (n = 67)

Study 2 (n = 78)

Study 3 (n = 99)

Study 4 (n = 71)

Total (N = 315)


Age (mean ± SD)

36.17 ± 11.14

39.56 ± 9.36

38.58 ± 11.95

41.77 ± 9.91

39.03 ± 10.84

Sex (Male %)

43(64.2)

57(73.1)

58(58.6)

53(74.6)

211(67.0)

Race (Caucasian %)*

54(80.6)

48(61.5)

53(53.5)

48(67.6)

203(64.4)

Diagnosis (%)

Schizophrenia

57(85.1)

54(69.2)

99(100)

39(54.9)

249(79.8)

Schizoaffective

8(11.9)

24(30.8)

--

32(45.1)

64(20.5)

Schizophreniform

2 (3.0)

--

--

--

2 (0.6)

Age of Onset Illness (yrs ± SD)

22.80 ± 6.69

21.63 ± 6.85

22.44 ± 7.62

22.63 ± 7.43

22.36 ± 7.18

PANSS Total (mean ± SD)

95.48 ± 15.31

86.60 ± 15.60

105.83 ± 22.04

82.01 ± 16.82

93.50 ± 20.35

Prior Hospitalization (%)*

65(97.0)

45(57.7)

27(27.3)

42(59.2)

179(56.8)

Hospitalization days (mean ± SD)

35.75 ± 54.52

73.11 ± 113.67

24.96 ± 69.32

49.14 ± 50.12

46.66 ± 76.40

Illness Duration (yrs ± SD)

13.25 ± 10.47

17.93 ± 9.53

16.13 ± 12.02

19.13 ± 10.83

16.65 ± 10.99


*Significantly different from all other patients (prior hospitalization, p = .007; Caucasian race, p < .0001).

Mean hospitalization days for group of patients reporting prior hospitalization.

Liu-Seifert et al. BMC Medicine 2005 3:21   doi:10.1186/1741-7015-3-21

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