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Baseline characteristics of patients who discontinued due to poor response or symptom worsening |
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| Characteristic |
Study 1 (n = 67) |
Study 2 (n = 78) |
Study 3 (n = 99) |
Study 4 (n = 71) |
Total (N = 315) |
|
|
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| Age (mean ± SD) |
36.17 ± 11.14 |
39.56 ± 9.36 |
38.58 ± 11.95 |
41.77 ± 9.91 |
39.03 ± 10.84 |
| Sex (Male %) |
43(64.2) |
57(73.1) |
58(58.6) |
53(74.6) |
211(67.0) |
| Race (Caucasian %)* |
54(80.6) |
48(61.5) |
53(53.5) |
48(67.6) |
203(64.4) |
| Diagnosis (%) |
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| Schizophrenia |
57(85.1) |
54(69.2) |
99(100) |
39(54.9) |
249(79.8) |
| Schizoaffective |
8(11.9) |
24(30.8) |
-- |
32(45.1) |
64(20.5) |
| Schizophreniform |
2 (3.0) |
-- |
-- |
-- |
2 (0.6) |
| Age of Onset Illness (yrs ± SD) |
22.80 ± 6.69 |
21.63 ± 6.85 |
22.44 ± 7.62 |
22.63 ± 7.43 |
22.36 ± 7.18 |
| PANSS Total (mean ± SD) |
95.48 ± 15.31 |
86.60 ± 15.60 |
105.83 ± 22.04 |
82.01 ± 16.82 |
93.50 ± 20.35 |
| Prior Hospitalization (%)* |
65(97.0) |
45(57.7) |
27(27.3) |
42(59.2) |
179(56.8) |
| Hospitalization days (mean ± SD)† |
35.75 ± 54.52 |
73.11 ± 113.67 |
24.96 ± 69.32 |
49.14 ± 50.12 |
46.66 ± 76.40 |
| Illness Duration (yrs ± SD) |
13.25 ± 10.47 |
17.93 ± 9.53 |
16.13 ± 12.02 |
19.13 ± 10.83 |
16.65 ± 10.99 |
|
*Significantly different from all other patients (prior hospitalization, p = .007; Caucasian race, p < .0001). † Mean hospitalization days for group of patients reporting prior hospitalization. | |||||
Liu-Seifert et al. BMC Medicine 2005 3:21 doi:10.1186/1741-7015-3-21 |
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