Table 3

Relative riska of first admission to hospital with 25 common categories of diagnosis/procedure, by BMI
RR (95% FCI) for incident hospital admissions in women with BMI (kg/m2) Number of hospital admissions
Reason for admission (ICD-10 diagnosis code(s) and/or OPCS-4 procedure code(s)) <22.5 22.5 to 24.9 25 to 29.9 30.0 to 34.9 35+ Trend (95%CI)/5 kg/m2
Circulatory disease
Ischemic heart disease (ICD-10: I20-I25) 0.83 (0.81-0.86) 4,561 1.0 (0.98-1.02) 7,591 1.24 (1.22-1.26) 12,836 1.45 (1.41-1.49) 5,262 1.60 (1.54-1.67) 2,233 1.25 (1.23-1.26) P <0.001
Atrial fibrillation (ICD-10: I48) 0.95 (0.91-1.00) 1,548 1.0 (0.96-1.04) 2,346 1.24 (1.20-1.28) 3,993 1.75 (1.67-1.82) 1,963 2.90 (2.74-3.07) 1,228 1.43 (1.40-1.46) P <0.001
Stroke (ICD-10: G45, I60-I69) 1.03 (0.99-1.07) 2,984 1.0 (0.97-1.03) 3,957 1.13 (1.10-1.15) 6,161 1.28 (1.23-1.33) 2,504 1.55 (1.46-1.64) 1,189 1.14 (1.12-1.16) P < 0.001
Venous thromboembolism (ICD-10: I26, I80-I82) 0.83 (0.79-0.88) 1,179 1.0 (0.96-1.05) 1,966 1.41(1.37-1.46) 3,754 2.07 (1.98-2.16) 1,941 3.05 (2.87-3.23) 1,126 1.53 (1.49-1.56) P <0.001
Varicose veins (OPCS-4: L84-L88) 0.95 (0.91-0.98) 2,901 1.0 (0.97-1.03) 4,378 1.04 (1.02-1.07) 6,067 0.96 (0.92-1.01) 1,997 0.80 (0.74-0.86) 676 0.98 (0.96-1.00) P = 0.03
Hemorrhoids (OPCS-4: H51-H53) 0.92 (0.88-0.96) 1,912 1.0 (0.96-1.04) 3,001 1.03 (1.00-1.06) 4,175 1.03 (0.97-1.08) 1,495 1.02 (0.94-1.11) 602 1.04 (1.01-1.06) P = 0.002
Respiratory disease
Pneumonia (ICD-10: J18)b 1.49 (1.43-1.55) 2,607 1.0 (0.96-1.04) 2,383 1.05 (1.02-1.09) 3,530 1.25 (1.19-1.32) 1,525 1.73 (1.62-1.85) 852 1.22 (1.19-1.26) P <0.001
Chronic obstructive pulmonary disease (ICD-10: J44)b 1.81 (1.74-1.89) 2,292 1.0 (0.95-1.05) 1,616 0.97 (0.93-1.01) 2,215 1.20 (1.12-1.28) 980 2.10 (1.95-2.27) 678 1.30 (1.25-1.34) P <0.001
Digestive disease
Diverticular disease (ICD-10:K57) 0.89 (0.86-0.91) 3,779 1.0 (0.98-1.03) 6,100 1.23 (1.21-1.26) 10,313 1.43 (1.38-1.47) 4,211 1.56 (1.49-1.63) 1,776 1.22 (1.20-1.24) P <0.001
Diaphragmatic hernia (ICD-10: K44) 0.78 (0.75-0.82) 2,635 1.0 (0.97-1.03) 4,758 1.28 (1.25-1.31) 8,250 1.49 (1.44-1.54) 3,466 1.37 (1.29-1.44) 1,294 1.23 (1.21-1.25) P <0.001
Peptic ulcer (ICD-10: K25-K28) 1.06 (1.01-1.12) 1,513 1.0 (0.96-1.05) 1,966 1.14 (1.10-1.18) 3,115 1.24 (1.17-1.31) 1,226 1.49 (1.37-1.62) 602 1.12 (1.09-1.14) P <0.001
Gallbladder disease (ICD-10: K80-K81; or OPCS-4: J18) 0.67 (0.65-0.70) 3,327 1.0 (0.98-1.02) 6,950 1.56 (1.53-1.58) 14,568 2.10 (2.05-2.15) 7,003 2.39 (2.30-2.47) 3210 1.50 (1.48-1.52) P <0.001
Musculo-skeletal disease
Wrist fracture (ICD-10: S52.5, S52.6, S62.0, S62.1, S62.8) 1.12 (1.08-1.17) 2,465 1.0 (0.97-1.04) 3,162 0.84 (0.81-0.87) 3,640 0.72 (0.68-0.76) 1,121 0.60 (0.54-0.66) 372 0.81 (0.79-0.83) P <0.001
Hip fracture (ICD-10: S72.0, S72.1, S72.2) 1.66 (1.59-1.73) 2,177 1.0 (0.95-1.05) 1,810 0.79 (0.76-0.83) 2,007 0.59 (0.54-0.65) 536 0.60 (0.52-0.69) 210 0.65 (0.63-0.67) P <0.001
Ankle fracture (ICD-10: S82.3, S82.5, S82.6, S82.8) 0.66 (0.62-0.70) 877 1.0 (0.96-1.05) 1,869 1.30 (1.26-1.35) 3,233 1.62 (1.53-1.71) 1,399 1.49 (1.37-1.63) 513 1.32 (1.29-1.36) P <0.001
Hip replacement (ICD-10: M16 and OPCS-4: W37.1, W38.1, W39.1) 0.74 (0.71-0.76) 2,544 1.0 (0.97-1.03) 4,953 1.26 (1.24-1.29) 8,542 1.71 (1.66-1.77) 4,006 2.05 (1.96-2.15) 1,804 1.39 (1.37-1.41) P <0.001
Knee replacement (ICD-10: M17 and OPCS-4: W40.1, W41.1, W42.1) 0.54 (0.51-0.58) 994 1.0 (0.96-1.04) 2,690 2.14 (2.09-2.18) 7,955 4.52 (4.41-4.64) 5,866 7.45 (7.21-7,71) 3,563 2.21 (2.18-2.24) P <0.001
Cancers
Non-melanoma skin cancer (ICD-10: C44) 1.10 (1.07-1.15) 3,008 1.0 (0.97-1.03) 3,910 0.86 (0.84-0.89) 4,575 0.85 (0.81-0.89) 1,563 0.77 (0.71-0.84) 541 0.88 (0.86-0.90) P <0.001
Benign colon cancer (ICD-10: D12) 0.97 (0.93-1.01) 2,388 1.0 (0.97-1.03) 3,422 1.06 (1.03-1.09) 4,881 1.13 (1.08-1.18) 1,831 1.15 (1.06-1.23) 730 1.06 (1.04-1.09) P <0.001
Breast cancer (ICD-10: C50) 0.93 (0.90-0.95) 6,101 1.0 (0.98-1.02) 9,051 1.07 (1.06-1.09) 12,644 1.14 (1.11-1.17) 4,623 1.18 (1.13-1.23) 1,888 1.09 (1.07-1.10) P <0.001
Other
Diabetes (ICD-10: E10-E11, E13-E14)c 0.56 (0.53-0.60) 1,109 1.0 (0.96-1.04) 2,732 2.36 (2.31-2.41) 8,964 5.67 (5.54-5.80) 7,530 11.62 (11.31-11.93) 5,720 2.53 (2.50-2.57) P < 0.001
Uterine fibroids (ICD-10: D25 and OPCS-4: Q10, Q18, Q074, Q089, or Q171) 0.85 (0.81-0.89) 1,532 1.0 (0.96-1.04) 2,360 1.09 (1.05-1.13) 3,071 1.18 (1.12-1.26) 1,119 1.22 (1.12-1.34) 498 1.13 (1.10-1.16) P < 0.001
Cataracts (ICD-10: H25-H26 or OPCS-4: C71-C75) 1.02 (1.00-1.04) 9,089 1.0 (0.98-1.02) 12,713 1.06 (1.05-1.08) 18,882 1.23 (1.20-1.26) 7,739 1.40 (1.35-1.45) 3,327 1.11 (1.10-1.12) P < 0.001
Female genital prolapse (ICD-10: N81 and OPCS-4: M51-M53, P22-P24) 0.73 (0.71-0.76) 4,187 1.0 (0.98-1.02) 8,480 1.09 (1.07-1.11) 12,815 0.99 (0.96-1.02) 4,264 0.70 (0.66-0.74) 1,223 1.04 (1.02-1.05) P < 0.001
Carpal tunnel syndrome (ICD-10: G56.0 or OPCS-4: A65.1) 0.79 (0.76-0.82) 2,874 1.0 (0.97-1.03) 5,076 1.32 (1.29-1.34) 8,851 1.80 (1.75-1.86) 4,287 2.44 (2.34-2.54) 2,346 1.43 (1.41-1.45) P < 0.001

aAdjusted for age, geographical region, socio-economic status, age at first birth, parity, smoking status, alcohol intake, physical activity and, where appropriate, time since menopause and HRT use; btrend estimated is based on women with a BMI of 22.5+ kg/m2; ccategorization based on any rather than primary diagnoses. BMI, body mass index; HRT, hormone replacement therapy; ICD-10, International Classification of Diseases, 10th revision; OPCS, Office of Population Censuses and Surveys classification of surgical operations and procedures, fourth revision; RR, relative risk.

Reeves et al.

Reeves et al. BMC Medicine 2014 12:45   doi:10.1186/1741-7015-12-45

Open Data