Table 1

Mean and median of autoantibodies' activity in celiac children, their parents compared to pediatric controls
Mean ± SD (median) Autoantibodies/groups
Parents versus pediatric control Pediatric celiac disease versus pediatric control Pediatric celiac disease versus parents Pediatric control (N = 88) Parents (N = 90) Pediatric celiac disease (N = 70)
ND ND ** ND 10.7 ±13.6 (8.2) 7.9 ±9.5 (5.6) aPS/PT IgA
** ** ** 3.6 ±2.5 (3.3) 16.1 ±15.9 (12.3) 32.4 ±19.5 (27.7) aPS/PT IgG
** ** ** 6.7 ±6.4 (4.9) 12.4 ±15.5 (8.6) 14.2 ±8.7 (12.9) aPS/PT IgM
* ** * 11.9 ±15.8 (6.0) 12.4 ±18.2 (7.9) 15.2 ±19.5 (10.6) Prothrombin IgG
** ** ** 9.4 ±7.0 (8.6) 8.0 ±10.4 (5.8) 10.4 ±6.0 (9.1) Phospholipid IgG
ND ND * ND 3.9 ±6.9 (1.7) 3.3 ±2.8 (2.5) Phospholipid IgM
NS NS ** 5.5 ±3.4 (4.9) 2.9 ±2.1 (2.2) 4.5 ±2.6 (4.4) Cardiolipin check

*P <0.001; ** P <0.0001; aPL: antiphospholipid; aPS/PT: antiphosphatidylserine/prothrombin; aPT: antiprothrombin; Ig: immunoglobulin; ND: not done NS: non-significant; SD: standard deviation.

Lerner et al.

Lerner et al. BMC Medicine 2013 11:89   doi:10.1186/1741-7015-11-89

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