Figure 1.

Mechanisms for VILI and potential targets for physiologic and non-physiologic interventions to minimize VILI. Reprinted with permission of the American Thoracic Society. Copyright (C) 2013 American Thoracic Society. Slutsky AS, Tremblay LN: Multiple system organ failure: is mechanical ventilation a contributing factor? Am J Resp Crit Care Med 1998, 157:17211725. ECLS, extracorporeal life support; LT, leukotrienes; MΦ, macrophages; NAVA, neurally adjusted ventilatory assist; PG, prostaglandins; ROS, reactive oxygen species; VILI, ventilator-induced lung injury.

Fan et al. BMC Medicine 2013 11:85   doi:10.1186/1741-7015-11-85
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