Table 4

Characteristics of the main Finnish Diabetes Risk Score (FINDRISC) cut-off points for screening-detected type 2 diabetes and glucose abnormalities (diabetes and pre-diabetes), classified by glucose and hemoglobin (Hb)A1c diagnostic criteria.

Cut-off values

n (%)

Diabetesa

Glucose abnormalitiesa


Sensitivity

Specificity

PPV

NPV

Sensitivity

Specificity

PPV

NPV


Diagnostic classification by the WHO criteria (2-hour plasma glucose)

6

31 (1.8)

100.0

4.3

9.6

100.0

99.3

5.4

32.5

94.0

10

111 (6.5)

94.9

19.7

11.7

97.5

90.9

22.6

35.0

84.4

13

166 (9.7)

81.0

42.1

12.5

95.6

73.2

46.0

38.3

78.9

14

139 (8.1)

75.9

52.3

13.9

95.5

65.8

56.7

41.1

78.4

15

156 (9.1)

69.6

60.6

15.2

95.1

59.7

65.8

44.4

78.1


Diagnostic classification by the ADA criteria (fasting plasma glucose)

6

31 (1.8)

100.0

4.0

3.2

100.0

99.2

5.1

29.2

94.0

10

111 (6.5)

100.0

18.9

3.8

100.0

92.6

22.7

32.1

88.5

13

166 (9.7)

84.9

40.7

4.4

98.8

75.3

46.0

35.5

82.5

14

139 (8.1)

75.5

50.5

4.6

98.5

68.0

56.6

38.3

81.8

15

156 (9.1)

67.9

58.6

5.0

98.3

61.6

65.4

41.4

81.2


Diagnostic classification by the HbA1c-based criteria

6

31 (1.8)

98.4

4.0

3.7

98.5

97.1

4.3

29.0

79.1

10

111 (6.5)

93.5

18.8

4.2

98.7

83.9

19.2

29.5

74.8

13

166 (9.7)

77.4

40.6

4.7

98.0

62.3

40.9

29.8

73.0

14

139 (8.1)

74.2

50.5

5.3

98.1

54.4

51.3

31.0

73.6

15

156 (9.1)

69.4

58.8

5.9

98.1

46.6

59.5

31.7

73.5


ADA, American Diabetic Association; Hb, hemoglobin; NPV, negative predictive value; PPV, positive predictive value.

aData on sensitivity, specificity, PPV and NPV are percentages.

Costa et al. BMC Medicine 2013 11:45   doi:10.1186/1741-7015-11-45

Open Data