Table 4

Plasma adrenocorticotropic hormone (ACTH) (pmol/l) and cortisol (nmol/l) tertiles and obesity comorbidities in logistic regression.

Factor

Tertile

ACTH

Cortisol


OR

95% CI

P value

OR

95% CI

P value


Hypertension

I

1.000

1.000

II

1.088

0.661 to 1.821

0.719

1.071

0.646 to 1.778

0.789

III

1.907

1.107 to 3.286

<0.02

1.721

1.008 to 2.913

<0.04

HDL <10° percentile

I

1.000

1.000

II

1.433

0.884 to 2.323

0.145

0.866

0.549 to 1.429

0.619

III

1.439

0.886 to 2.338

0.141

1.993

0.610 to 1.614

0.976

TG >90° percentile

I

1.000

1.000

II

1.182

0.631 to 2.212

0.601

0.981

0.545 to 1.768

0.950

III

2.367

1.319 to 4.248

<0.004

1.410

0.798 to 1.491

0.237

LDL >90° percentile

I

1.000

1.000

II

2.181

0.655 to 7.263

0.204

2.520

0.676 to 7.490

0.186

III

3.098

0.973 to 9.866

0.056

3.223

1.012 to 10.265

<0.04

Dysglycemia

I

1.000

1.000

II

1.659

0.632 to 4.356

0.304

1.161

0.484 to 2.788

0.738

III

2.959

1.198 to 7.307

<0.01

1.699

0.740 to 3.900

0.211

Hypertensiona

I

1.000

1.000

II

1.033

0.603 to 1.769

0.906

1.042

0.607 to 1.790

0.882

III

1.668

0.978 to 2.966

0.072

1.593

1.002 to 3.133

<0.04

HDL <10° percentilea

I

1.000

1.000

II

1.287

0.771 to 2.148

0.335

0.817

0.489 to 1.365

0.440

III

1.090

0.649 to 1.832

0.745

0.868

0.514 to 1.467

0.598

TG >90° percentilea

I

1.000

1.000

III

1.050

0.546 to 2.019

0.884

1.075

0.578 to 2.000

0.819

III

2.118

1.139 to 3.939

<0.01

1.559

0.851 to 2.856

0.150

LDL >90° percentilea

I

1.000

1.000

II

2.279

0.678 to 7.665

0.183

2.286

0.678 to 7.725

0.183

III

3.179

0.975 to10.365

0.055

3.546

1.095 to 11.490

<0.03

Dysglycemiaa

I

1.000

1.000

II

1.582

0.593 to 4.217

0.359

1.040

0.421 to 2.570

0.932

III

2.548

1.003 to 6.475

<0.04

1.516

0.641 to 3.585

0.344


Values in bold represent significant results. Hypertension was considered as >95° percentile. aAdjusted for gender, age, Tanner stage, and BMI. ACTH tertiles were subdivided as: I = <3.54 pmol/l; II = 3.54 to 5.92 pmol/l; III = >5.92 pmol/l. Cortisol tertiles were subdivided as: I = <240.0 nmol/l; II = 240.0 to 383.5 nmol/l; III = >383.5nmol/l. BMI = body mass index; CI = confidence interval; HDL = high-density lipoprotein; LDL = low-density lipoprotein; OR = odds ratio; TG = triglycerides.

Prodam et al. BMC Medicine 2013 11:44   doi:10.1186/1741-7015-11-44

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