Table 3

Partial correlation for adrenocorticotropic hormone (ACTH) (pmol/l) and cortisol (nmol/l) with cardiovascular risk factors.

Model and factor

ACTH

Cortisol


r

P value

r

P value


Model 1

SBP, mmHg

0.098

0.052

0.121

<0.01

DBP, mmHg

0.105

<0.03

0.119

<0.01

HDL, mmol/l

-0.016

0.753

0.040

0.432

TG, mmol/l

0.144

<0.004

0.107

<0.03

LDL, mmol/l

-0.002

0.961

0.123

<0.01

Glc0', mmol/l

0.248

<0.0001

0.110

<0.02

Glc120', mmol/l

0.144

<0.02

-0.020

0.712

Ins0', pmol/l

0.122

<0.01

0.050

0.327

HOMA-IR

0.152

<0.003

0.065

0.200

Model 2

SBP, mmHg

0.100

<0.05

0.112

<0.03

DBP, mmHg

0.106

<0.04

0.124

<0.01

HDL, mmol/l

-0.013

0.796

0.048

0.353

TG, mmol/l

0.128

<0.01

0.102

<0.04

LDL, mmol/l

-0.019

0.712

0.116

<0.02

Glc0', mmol/l

0.218

<0.0001

0.117

<0.02

Glc120', mmol/l

0.128

<0.04

-0.030

0.638


Values in bold represent significant results. Partial correlation was adjusted for gender, age, Tanner stage, and BMI in model 1 and for gender, age, Tanner stage, BMI, and insulin resistance in model 2. Log transformation was used for skewed variables. DBP = diastolic blood pressure; Glc0' = fasting glucose; Glc120' = post-challenge glucose; HDL = high-density lipoprotein; HOMA-IR = homeostatic model assessment insulin resistance; Ins0' = fasting insulin; LDL = low-density lipoprotein; SDB = systolic blood pressure; TG = triglycerides.

Prodam et al. BMC Medicine 2013 11:44   doi:10.1186/1741-7015-11-44

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