Expression of hypoxia-induced mRNA in maternal blood from women in labor. (A) Cluster analysis and heatmap of 41 hypoxia induced transcripts in maternal blood sampled moments before delivery from the hypoxia cohort (umbilical artery lactate concentrations sampled at birth were >6.0 mmol/L) or controls (umbilical artery lactate <6.0 mmol/L). Green indicates increased expression, red is decreased expression. (B) Hypoxia inducible factor (Hif)1α, Hif2α, adrenomedullin (Adm) and lactate dehydrogenase A (LdhA) expression in maternal blood sampled moments before birth from the hypoxia cohort (n = 14) or controls (n = 16). Mean and S.E.M. are graphed. *P <0.05. **P <0.01. ***P <0.001.
Whitehead et al. BMC Medicine 2013 11:256 doi:10.1186/1741-7015-11-256