Table 4

Risk of acute myocardial infarction (separate fatal and non-fatal) by dietary n-3 LCPUFA tertiles (as a percentage of total energy intake)
Non-diabetes (HbA1c <5.7%, n = 1,012) Pre-diabetes (HbA1c ≥5.7%, n = 1,049) Diabetes (n = 317)a
Fatal AMI (events) 16 20 18
Tertile 1b 1.00 1.00 1.00
Tertile 2c 1.98 (0.36, 10.82) 1.85 (0.56, 6.15) 0.39 (0.13, 1.15)
Tertile 3d 4.79 (1.05, 21.90) 1.84 (0.56, 6.13) 0.22 (0.06, 0.81)
P for trend 0.02 0.34 0.02
Non-fatal AMI (events) 61 68 25
Tertile 1b 1.00 1.00 1.00
Tertile 2c 1.03 (0.55 to 1.93) 1.04 (0.58 to 1.87) 0.45 (0.17 to 1.20)
Tertile 3d 1.10 (0.60 to 2.04) 1.04 (0.58 to 1.86) 0.52 (0.20 to 1.32)
P for trend 0.75 0.91 0.14

Hazard ratios and 95% confidence intervals were calculated using Cox proportional hazards. The model was adjusted for age (continuous) and sex. aDiabetes was defined as clinically diagnosed, or as having a fasting glucose ≥7.0 or a non-fasting glucose ≥11.1 mmol/L. bn = 337 in non-diabetic, n = 349 in pre-diabetic, and n = 105 in diabetic patients. cn = 338 in non-diabetic, n = 350 in pre-diabetic, and n = 106 in diabetic patients. dn = 337 in non-diabetic, n = 350 in pre-diabetic, and n = 106 in diabetic patients. HbA1c, glycosylated hemoglobin; n-3 LCPUFA, n-3 long-chain polyunsaturated fatty acids (eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid).

Strand et al.

Strand et al. BMC Medicine 2013 11:216   doi:10.1186/1741-7015-11-216

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