Table 1 |
||
| Phenomenological similarities between encephalomyelitis disseminata/multiple sclerosis (MS) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) | ||
| Phenomenology | MS | ME/CFS |
| Disabling fatigue | ✓ | ✓ |
| Severe exercise intolerance | ✓ | ✓ |
| Mental fatigue | ✓ | ✓ |
| ‘Pacing’ as an energy conservation strategy | ✓ | ✓ |
| Worsening of symptoms following exercise | ✓ | ✓ |
| Orthostatic intolerance | ✓ | ✓ |
| Gastrointestinal dysfunction | ✓ | ✓ |
| Cardiac dysrhythmias | ? | ✓ |
| Postural hypotension | ✓ | ✓ |
| Diminished cardiac response to exercise | ✓ | ✓ |
| Relapsing-remitting nature | ✓ | ✓ |
| Chronic course | ✓ | ✓ |
| Disease exacerbated by infections | ✓ | ✓ |
| Disease exacerbated by psychological stress | ✓ | ✓ |
| Disease worsened or precipitated by infections | ✓ | ✓ |
Morris and Maes
Morris and Maes BMC Medicine 2013 11:205 doi:10.1186/1741-7015-11-205