Table 3

Baseline characteristics of non-smokers, former smokers and current smokers
Smoking status Men Women
Non-smoker Former smoker Current smoker Pvalue Non-smoker Former smoker Current smoker Pvalue
n (%) 10,529 (43.2%) 8,175 (33.5%) 5,685 (23.3%) 16,456 (46.9%) 11,633 (33.2%) 6,989 (19.9%)
Age, years 42 ± 11 51 ± 12 43 ± 11 <0.001 43 ± 12 48 ± 11 42 ± 11 <0.001
BMI, kg/m2 26.1 ± 3.7 27.0 ± 3.5 26.2 ± 3.7 <0.001 25.6 ± 4.8 26.3 ± 4.7 25.4 ± 4.6 <0.001
BMI ≥30 kg/m2, n (%) 1,311 (12.5%) 1,390 (17.0%) 812 (14.3%) 2,623 (15.9%) 2,087 (17.9%) 951 (13.6%)
SBP, mmHg 130 ± 13 133 ± 14 131 ± 13 <0.001 122 ± 15 124 ± 16 121 ± 14 <0.001
DBP, mmHg 76 ± 9 78 ± 9 76 ± 9 <0.001 72 ± 9 73 ± 9 72 ± 9 <0.001
Total cholesterol, mmol/l 5.0 ± 1.0 5.2 ± 1.0 5.1 ± 1.0 <0.001 4.9 ± 1.0 5.1 ± 1.0 5.0 ± 1.0 <0.001
LDL-C, mmol/l 3.28 ± 0.86 3.43 ± 0.89 3.39 ± 0.92 <0.001 2.99 ±0.85 3.18 ± 0.89 3.14 ± 0.92 <0.001
HDL-C, mmol/l 1.31 ± 0.31 1.31 ± 0.32 1.21 ± 0.30 <0.001 1.59 ± 0.38 1.65 ± 0.40 1.49 ± 0.38 <0.001
Triglycerides, mmol/la 1.12 (0.78 to 1.54) 1.25 (0.87 to 1.73) 1.35 (0.92 to 1.91) <0.001 0.87 (0.64 to 1.16) 0.93 (0.68 to 1.25) 1.01 (0.73 to 1.36) <0.001
Apolipoprotein A1, g/l 1.43 ± 0.22 1.46 ± 0.22 1.40 ± 0.22 <0.001 1.61 ± 0.27 1.66 ± 0.27 1.57 ± 0.28 <0.001
HDL-C/apoA1 ratio 0.89 ± 0.13 0.88 ± 0.13 0.85 ± 0.13 <0.001 0.97 ± 0.14 0.98 ± 0.60 0.92 ± 0.13 <0.001
Apolipoprotein B, g/l 0.94 ± 0.23 1.00 ± 0.24 1.00 ± 0.25 <0.001 0.87 ± 0.23 0.91 ± 0.23 0.93 ± 0.24 <0.001
LDL-C/apoB ratio 3.49 ± 0.37 3.45 ± 0.41 3.37 ± 0.40 <0.001 3.44 ± 0.37 3.47 ± 0.36 3.38 ± 0.36 <0.001
Blood glucose, mmol/la 5.05 (4.70 to 5.30) 5.26 (4.90 to 5.50) 5.11 (4.70 to 5.40) <0.001 4.83 (4.50 to 5.10) 4.94 (4.60 to 5.20) 4.84 (4.50 to 5.10) <0.001
Waist circumference, cm 94 ± 11 98 ± 10 95 ± 11 <0.001 86 ± 12 89 ± 12 87 ± 12 <0.001
BP-lowering medication, n (%) 821 (7.8%) 1,497 (18.3%) 503 (8.8%) <0.001 1,683 (10.2%) 1,660 (14.3%) 621 (8.9%) <0.001
Statin use, n (%) 411 (3.9% 918 (11.2% 419 (7.4%) <0.001 560 (3.4%) 594 (5.1%) 275 (3.9%) <0.001
TG-lowering medication, n (%) 13 (0.1%) 24 (0.3%) 14 (0.2%) NS 6 (0.1%) 10 (0.1%) 6 (0.1%) NS
Type 2 diabetes, n (%) 113 (1.1%) 264 (3.2%) 83 (1.5%) <0.001 188 (1.1%) 216 (1.9%) 68 (1.0%) NS
Oral antihyperglycemic medication, n (%) 102 (1.0%) 217 (2.7%) 69 (1.2%) <0.001 154 (0.9%) 164 (1.4%) 55 (0.8%) <0.001

Data are presented as mean ± SD, or median (interquartile range).

aData given as geometric mean (interquartile range).

Apo apolipoprotein, BMI body mass index, BP blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, NS not significant, SBP systolic blood pressure, TG triglycerides.

Slagter et al.

Slagter et al. BMC Medicine 2013 11:195   doi:10.1186/1741-7015-11-195

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